Understanding the Link Between Diet and Lung Cancer Risk
Recent research has uncovered a significant connection between diet and lung cancer risk, particularly highlighting the role of ultraprocessed foods. This new study adds to the growing body of evidence suggesting that what people eat can influence their likelihood of developing this deadly disease.
What Are Ultraprocessed Foods?

Ultraprocessed foods are defined as those that contain ingredients not typically used in home cooking, such as preservatives, artificial colors, emulsifiers, and added sugars or salts. These items often include sodas, chips, packaged soups, chicken nuggets, and ice cream. The processing methods used in these foods can alter their nutritional profile and introduce harmful substances.
According to the Food and Agriculture Organization of the United Nations, these foods are designed to be highly palatable and appealing, often through the use of additives that enhance flavor, texture, and shelf life. However, this convenience comes with potential health risks.
Study Findings on Lung Cancer and Diet
The study published in the journal Thorax found that individuals who consumed the highest amounts of ultraprocessed foods were 41% more likely to be diagnosed with lung cancer compared to those who ate the least. This association remained even after accounting for other factors such as smoking.
Researchers analyzed data from over 100,000 participants who completed the National Health and Nutrition Examination Survey’s Food Frequency Questionnaire. They found that the average person consumed nearly three servings of ultraprocessed foods daily, with common items including lunch meats, diet or caffeinated soft drinks, and decaffeinated soft drinks.
Possible Mechanisms Behind the Link
The researchers suggested that industrial processing alters the food matrix, affecting nutrient availability and absorption. They also noted the presence of harmful contaminants like acrolein, which can come from various sources, including burning tobacco, wood, plastics, gasoline, and cooking fats at high temperatures.
Additionally, packaging materials may contribute to the problem, according to the study authors. While the study is observational and cannot definitively prove causation, it strongly suggests that ultraprocessed foods may contribute to lung cancer risk.
The Role of Diet Quality in Health
Dr. David Katz, a specialist in preventive and lifestyle medicine, emphasized the importance of diet quality in predicting premature death from all causes in the United States. He pointed out that ultraprocessed foods are often associated with lower diet quality, characterized by higher intake of saturated fats, chemicals, salt, and sugar, as well as higher calorie consumption.
These factors can drive inflammation, a primary pathway in the development and progression of cancer, and damage the microbiome, impairing immune system function. This combination of excess inflammation and impaired immunity gives rogue cells the upper hand, potentially leading to cancer.
Other Factors Influencing Lung Cancer Risk
Lung cancer is not solely linked to smoking, although it remains the main contributor. According to the World Health Organization, there were an estimated 2.4 million new cases worldwide in 2022. People who don’t smoke can still develop lung cancer, indicating that other factors play a role.
The study authors adjusted for factors such as smoking, but Dr. Fang Fang Zhang, a professor at Tufts University, noted that the measurements were not nuanced. She highlighted the importance of adjusting for the intensity and duration of smoking, as well as cumulative exposure, to better understand the relationship between ultraprocessed foods and lung cancer risk.
The Impact of Additives and Packaging
Additives in ultraprocessed foods, carcinogens formed during processing, and chemicals from food packaging might also contribute to lung cancer risk. However, these pathways are not yet fully understood and require further investigation.
Dr. Tom Brenna, a professor at the University of Texas at Austin, explained that omega-3s, essential healthy fats, are often removed during processing because they limit shelf life. This loss of beneficial nutrients could exacerbate the negative effects of ultraprocessed foods.
Recommendations for a Healthier Diet
To reduce the risk of lung cancer and improve overall health, experts recommend increasing the consumption of whole, unprocessed foods. This includes vegetables, fruits, whole grains, beans, lentils, nuts, and seeds.
Dr. Katz advised starting by reading food labels and avoiding foods with long ingredient lists that contain unfamiliar names, which are more likely to be additives, preservatives, and artificial flavors. He also encouraged prioritizing whole foods and preparing meals using minimally processed ingredients whenever possible.
Transitioning to a Healthier Lifestyle
Making dietary changes can be challenging, especially for those accustomed to eating a lot of ultraprocessed foods. However, gradual transitions can help. Dr. Katz suggested replacing one ultraprocessed food with a healthier alternative at a time, allowing taste buds to adjust over a few weeks.
Once individuals become accustomed to the taste of more natural ingredients, maintaining a healthier diet becomes easier. This shift not only improves health but also enhances the overall quality of life.